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Year : 2021  |  Volume : 22  |  Issue : 1  |  Page : 62-65

A Challenging Case of Toxic Epidermal Necrolysis in a 2 Year Old Child With Review of Literature

1 Department of Dermatology, Venereology and Leprosy, Army College of Medical Sciences, Delhi, India
2 Department of Paediatrics, Army College of Medical Sciences, Delhi, India
3 Base Hospital Delhi Cantt, Delhi, India
4 DNB Resident, Base Hospital Delhi Cantt, Army College of Medical Sciences, Delhi, India

Correspondence Address:
Barnali Mitra
Associate Prof, Department of Paediatric, Base Hospital Delhi Cantt & Army College of Medical science, Delhi - 110 010
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijpd.IJPD_64_20

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Toxic epidermal necrolysis (TEN) is a rare, severe, life-threatening, mucocutaneous adverse drug reaction characterized by widespread blistering and sloughing of the epidermis and mucositis with fatal complications such as sepsis and multiorgan failure. In most cases, drugs are implicated, but occasionally, vaccination and infection can be the triggers of TEN. TEN is very rare in infants and young children and usually has a fatal outcome due to sepsis or multiorgan failure due to large body surface area. Till now, only a few reports have been documented in the literature. We hereby report a challenging case of TEN in a 2-year-old boy who had had a turbulent course during his hospital admission. He was successfully treated with intravenous immunoglobulin followed by systemic steroid along with high-end systemic antibiotics in a dedicated dermatology intensive care setup taking care of his fluid, electrolytes, calories, protein demand, and care of skin and mucosa.

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