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Year : 2017  |  Volume : 18  |  Issue : 3  |  Page : 155-159

Cutaneous manifestations of primary immunodeficiency

Department of Pediatrics, Stony Brook University Hospital, Stony Brook, New York, USA

Correspondence Address:
Ratna B Basak
Department of Pediatrics, Stony Brook University Hospital, Stony Brook, New York
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijpd.IJPD_10_17

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Primary immunodeficiency diseases (PIDs) are a group of rare, chronic disorders with deficient or malfunctioning immune system. It commonly affects the hematopoietic system, with skin the second most affected organ. Skin involvement is observed in half of pediatric PID cases and often precedes the final diagnosis. Skin infections and eczemas are the two most common manifestations in PID.[1] Skin manifestations associated with PIDs can be of infectious and noninfectious causes. Common noninfectious causes are eczema, erythroderma, cutaneous granulomas, dysplasia, vasculitis, and telangiectasia. It is important to be aware of skin manifestations in pediatric patients as early detection of PID may aid in the management of serious immunologic conditions and prevent associated morbidity and mortality.

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