Indian Journal of Paediatric Dermatology

CASE REPORT
Year
: 2019  |  Volume : 20  |  Issue : 3  |  Page : 267--270

A rare phenomenon of twin spotting: Phacomatosis pigmentokeratotica


Vaishali Wankhade, Vrutika Hasmukh Shah, Rajesh P Singh, Jayesh Mukhi 
 Department of Dermatology, Venereology and Leprosy, Government Medical College, Nagpur, Maharashtra, India

Correspondence Address:
Dr. Vrutika Hasmukh Shah
B.1103, Apollo Pride Enclave Complex, Next to Thane Bharat Sahakari Bank, Baji Prabhu Deshpande Marg, Vishnunagar, Thane West, Thane - 400 602, Maharashtra
India

Phacomatosis pigmentokeratotica is a rare form of cutaneous mosaicism characterized by epidermal nevus usually nevus sebaceous, papular speckled lentiginous nevus, and extracutaneous anomalies. This type of twin-spot phenomenon (didymosis) is due to postzygotic crossing-over resulting in two homozygous daughter cells, representing the stem cells of the two distinct types of nevi and leading to additional extracutaneous defects. We report a case of this rare syndrome in a 4-year-old male child associated with skeletal anomalies.


How to cite this article:
Wankhade V, Shah VH, Singh RP, Mukhi J. A rare phenomenon of twin spotting: Phacomatosis pigmentokeratotica.Indian J Paediatr Dermatol 2019;20:267-270


How to cite this URL:
Wankhade V, Shah VH, Singh RP, Mukhi J. A rare phenomenon of twin spotting: Phacomatosis pigmentokeratotica. Indian J Paediatr Dermatol [serial online] 2019 [cited 2019 Dec 5 ];20:267-270
Available from: http://www.ijpd.in/article.asp?issn=2319-7250;year=2019;volume=20;issue=3;spage=267;epage=270;aulast=Wankhade;type=0