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Year : 2019  |  Volume : 20  |  Issue : 2  |  Page : 145-147

Vincristine, aspirin, and prednisolone therapy in Kasabach–Merritt phenomenon: Response in 2 cases

1 Department of Dermatology, Chacha Nehru Bal Chikitsalaya, Delhi, India
2 Department of Dermatology, MIMER Medical College, Talegaon Dabhade, Maharashtra, India
3 Department of Surgery, Chacha Nehru Bal Chikitsalaya, Delhi, India
4 Department of Pathology, Chacha Nehru Bal Chikitsalaya, Delhi, India

Correspondence Address:
Dr. Shikha Gupta
Department of Dermatology, Chacha Nehru Bal Chikitsalaya, Delhi
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijpd.IJPD_18_18

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Kasabach–Merritt phenomenon (KMP) is a severe thrombocytopenic coagulopathy which usually occurs in the presence of enlarging vascular tumors such as kaposiform hemangioendothelioma (KHE) and tufted angioma. The treatment for this potentially fatal condition is challenging without a consensus on appropriate management. The authors report two cases of KHE with KMP, wherein improvement in size of tumor and coagulopathy occurred after treatment with prednisolone, vincristine, and aspirin.

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