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REVIEW ARTICLE
Year : 2015  |  Volume : 16  |  Issue : 1  |  Page : 5-8

Antiphospholipid antibody syndrome in pediatric population: An overview


1 Department of Dermatology, Venereology and Leprosy, Bangalore Medical College and Research Institute, Bengaluru, Karnataka, India
2 Department of Paediatric Dermatology, Institute of Child Health, Talegaon Dabhade, Pune, Maharashtra, India
3 Department of Dermatology, Venereology and Leprosy, M.I.M.E.R. Medical College, Talegaon Dabhade, Pune, Maharashtra, India
4 Pediatric Dermatology Unit, Rita Skin Foundation, Kolkata, West Bengal, India

Correspondence Address:
Samipa S Mukherjee
Department of Dermatology, Venereology and Leprosy, Bangalore Medical College and Research Institute, Bangalore, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2319-7250.149401

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The antiphospholipid (APL) antibody syndrome is an autoimmune conditions characterized by recurrent thromboembolic events. The exact incidence of its occurrence in the pediatric age group in Indian population is not known. Due to the higher incidence of infections in this age group there is a higher incidence of APL antibodies (APLAs) while the patients are asymptomatic, thereby making the establishment of diagnosis challenging. Secondary APL antibody syndrome is associated with underlying systemic lupus erythematosus. Due to the higher incidence of positivity of APLAs in children it is advised to conduct the diagnostic tests twice. Varying cutaneous features and lack of adequate awareness regarding the presenting signs and symptoms in pediatric population makes the diagnosis difficult. There are no guidelines for the management of this condition in children and it is extrapolated from the guidelines used in the adults. Early detection of this condition helps in reducing morbidity and improving the care and management of the patient.


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