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REVIEW ARTICLE
Year : 2013  |  Volume : 14  |  Issue : 3  |  Page : 54-61

Atopic dermatitis and tacrolimus: Current perspectives


Department of Dermatology, Venereology and Leprosy, Muzaffarnagar Medical College and Hospital, Muzaffarnagar, Uttar Pradesh, India

Correspondence Address:
Tarang Goyal
Department of Dermatology, Venereology and Leprosy, Muzaffarnagar Medical College and Hospital, Muzaffarnagar - 251 203, Uttar Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2319-7250.122163

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The purpose of the following study is to convey the range of current understanding in relation to atopic dermatitis (AD) and tacrolimus. A brief structured description is given starting with introducing the subject and continuing with the discussion of the etiology of AD, a comparative evaluation of the diagnostic criteria, presents management algorithm, structure, pharmacodynamics and pharmacokinetics of topical calcineurin inhibitors (TCI) and the comparative efficacy and safety of available TCIs. Etiological hypothesis is still evolving. Until date, no single universally applicable diagnostic Criteria or scoring system exists. Diagnostic Criteria and scoring system are to adopt according the design and population of any study. TCIs provide a safe alternate to the present topical steroid dependent system of management of AD. This is not a systemic review or meta-analysis. The studies cited were not compared statistically. Beneficial to practitioners of pediatric dermatology to get an idea about the range of current understandings.


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