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Year : 2012  |  Volume : 13  |  Issue : 1  |  Page : 27-33

Vitiligo: Newer insights in pathophysiology and treatment

Department of Internal Medicine, Medwin Hospital, Nampally, Hyderabad, Andhra Pradesh, India

Correspondence Address:
Dilip Gude
Intensivist & Research Coordinator, Department of Internal Medicine/Critical care, Princess Durru-Shehvar Children's and General Hospital, Purani Haveli, Hyderabad, Andhra Pradesh
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Source of Support: None, Conflict of Interest: None

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Despite decades of studies, vitiligo still evades us its exact pathophysiology and remains a challenge for clinicians. With a devastating cosmetic impact, the implications on the patient are dispiriting. A combination of the different proposed hypotheses may be responsible for its pathophysiologic basis. A variety of hypotheses that included autoimmune, neural, self-destruct and biochemical means to explain the pathophysiologic basis of vitiligo were proposed. But they are increasingly giving way to newer theories that better delineate the basis of the disease and have paved way for different advancements in treatment accordingly. Our newer management modalities have bolstered our weaponry in fighting vitiligo. A review of the newer insights in to the pathophysiology and management of vitiligo is presented.

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